TIF1γ/TRIM33 Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3140
TIF1γ/TRIM33 Mouse mAb (AB3140)
UniProt:Q9UPN9
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3140
Data Sheet
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UniProt
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Mol Weight140KDa
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Alternative NamesTRIM33; Ectodermin homolog; ECTO; RET-FUSED GENE 7; RFG7; TF1G; TIF1-gamma; PTC7; TIF1G; Tripartite motif-containing 33; Protein Rfg7; Tripartite motif containing 33
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ImmunogenPurified recombinant human TIF1 gamma / TRIM33 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2a
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ClonalityMonoclonal
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DescriptionActs as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:1000