BRG1 Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3133
BRG1 Mouse mAb (AB3133)
UniProt:P51532
Application:WB,IP
Reactivity:Human
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3133
Data Sheet
-
UniProt
-
Mol Weight220KDa
-
Alternative NamesATP-dependent helicase SMARCA4; BRG1-associated factor 190A; BAF190A; Mitotic growth and transcription activator; Protein BRG-1; Protein brahma homolog 1; SNF2-beta;
-
ImmunogenPurified recombinant human BRG1 protein fragments expressed in E.coli.
-
StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeMouse IgG1
-
ClonalityMonoclonal
-
DescriptionTranscriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation.Component of the CREST-BRG1 complex,a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex.In resting neurons,transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex.
Applications
-
ReactivityHuman
-
ApplicationWB,IP
-
Recommended dilutionWB 1:1000 IP