PRMT6 Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3120
PRMT6 Mouse mAb (AB3120)
UniProt:Q96LA8
Application:WB,IHC,ICC/IF
Reactivity:Human
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3120
Data Sheet
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UniProt
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Mol Weight42KDa
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Alternative NamesChromobox protein homolog 7; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 6; Histone-arginine N-methyltransferase PRMT6;
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ImmunogenPurified recombinant human PRMT6 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionIt thereby acts as a transcription corepressor of various genes such as HOXA2. Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to stimulate the polymerase activity by enhancing DNA binding and processivity.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000 IHC 1:200 ICC/IF 1:300
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Western blot detection of PRMT6 in Hel and 293T cell lysates using PRMT6 mouse mAb (1:1000 diluted).Predicted band size: 42KDa.Observed band size: 42KDa. -
Immunohistochemistry stain of paraffin-embedded human breast cancer using PRMT6 mouse mAb (1:200). -
Immunofluorescent analysis stain of Hela using PRMT6 mouse mAb (1:300).
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