NPM1 Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3115
NPM1 Mouse mAb (AB3115)
UniProt:P06748
Application:WB
Reactivity:Human,Mouse
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3115
Data Sheet
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UniProt
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Mol Weight38KDa
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Alternative NamesNPM isoform 1; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin; nucleophosmin;
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ImmunogenPurified recombinant full length of human NPM1 protein expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionInvolved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4.
Applications
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ReactivityHuman,Mouse
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ApplicationWB
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Recommended dilutionWB 1:1000
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Western blot detection of NPM1 in Hela,Jurkat and 3T3 cell lysates using NPM1 mouse mAb (1:1000 diluted).Predicted band size:33KDa.Observed band size:38KDa.
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