PRMT4/CARM1 Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3112
PRMT4/CARM1 Mouse mAb (AB3112)
UniProt:Q86X55
Application:WB,IP
Reactivity:Human,Mouse
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3112
Data Sheet
-
UniProt
-
Mol Weight63KDa
-
Alternative NamesHistone arginine methyltransferase CARM 1; Histone arginine methyltransferase CARM1; PRMT4; Protein arginine N methyltransferase 4;
-
ImmunogenPurified recombinant human PRMT4/CARM1 protein fragments expressed in E.coli.
-
StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeMouse IgG1
-
ClonalityMonoclonal
-
DescriptionMethylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling.
Applications
-
ReactivityHuman,Mouse
-
ApplicationWB,IP
-
Recommended dilutionWB 1:200-500 IP
-
Western blot detection of PRMT4/CARM1 in Hela,A431 and K562 cell lysates using PRMT4/CARM1 mouse mAb (1:200-1:500 diluted).Predicted band size:63KDa.Observed band size:63KDa. -
Immunoprecipitation analysis of Hela cell lysates using PRMT4/CARM1 mouse mAb.
Communicate
One click phone