DBC1 Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3109
DBC1 Mouse mAb (AB3109)
UniProt:Q8N163
Application:WB,ICC/IF,IP
Reactivity:Human,Mouse,Rat,Monkey
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3109
Data Sheet
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UniProt
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Mol Weight130KDa
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Alternative NamesDBCCR1; Deleted in bladder cancer protein 1 recursor; FAM5A;
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ImmunogenPurified recombinant human DBC1 protein fragments expressed in E.coli
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionInhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis.Inhibits SUV39H1 methyltransferase activity.As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
Applications
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ReactivityHuman,Mouse,Rat,Monkey
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ApplicationWB,ICC/IF,IP
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Recommended dilutionWB 1:500 ICC/IF 1:200 IP
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Western blot detection of DBC1 in HeLa,A549,Jurkat,C6,3T3 and COS7 cell lysates using DBC1 mouse mAb (1:500 diluted).Predicted band size:130KDa.Observed band size:130KDa.
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Immunofluorescent analysis of HeLa cells using anti-DBC1 mouse mAb diluted 1:200.
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Immunoprecipitation analysis of Hela cell lysates using DBC1 mouse mAb.