Lamin B1 Antibody
Source: Tags and Loading Controls Catalog No. : AB0054
Lamin B1 Antibody (AB0054)
UniProt:P20700
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（13）
http://www.abways.com/showproduct.asp?cid=AB0054
Data Sheet
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UniProt
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Mol Weight70kDa
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Alternative NamesLMN; ADLD; LMN2; LMNB; Lamin B1;
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ImmunogenA synthesized peptide derived from human Lamin B1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:3000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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Immunohistochemical analysis of paraffin-embedded Rat ovary, using the Antibody at 1:200 dilution. -
Immunohistochemical analysis of paraffin-embedded Human non-Hodgkin's lymphoma, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human glioblastoma, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:100 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution. -
All lanes use AB0054 Lamin B1 Antibody at 1:10000 dilution for 1 hour at room temperature. -
All lanes use AB0054 Lamin B1 Antibody at 1:20000 dilution for 1 hour at room temperature. -
All lanes use AB0054 Lamin B1 Antibody at 1:10000 dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded rat liver, using Lamin B1 Antibody. -
Immunofluorescent analysis of HepG2 cells, using Lamin B1 Antibody. -
Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells. -Journal of Affective Disorders
References （13）
Euphorbia factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation in mice through the suppression of NF-κB activation.-Biochemical Pharmacology
Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells.-Journal of Affective Disorders
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus - 2021.9-Cell Death and Differentiation
Overexpression of ARHGAP30 suppresses growth of cervical cancer cells by downregulating ribosome biogenesis-CANCER SCIENCE (CANCER SCI)
Ulmoidol, an unusual nortriterpenoid from Eucommia ulmoides Oliv. Leaves prevents neuroinflammation by targeting the PU.1 transcriptional signaling pathway-Bioorganic Chemistry (BIOORG CHEM)
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